ea0013p171 | Diabetes, metabolism and cardiovascular | SFEBES2007
Konopelska Sarah
, Kienitz Tina
, Pirlich Matthias
, Bauditz Juergen
, Stewart Paul M
, Hughes Beverly
, Lochs Herbert
, Strasburger Christian J
, Quinkler Marcus
Background: Non-alcoholic fatty liver disease (NAFLD) is recognized as common liver disorder that represents the hepatic manifestation of the metabolic syndrome including visceral obesity, type 2 diabetes, insulin resistance and hyperlipidemia. Non-alcoholic steatohepatitis (NASH) is the progressive form of liver injury with the risk for progressive fibrosis, cirrhosis and end-stage liver disease. The pathophysiology that leads to NAFLD and NASH is not well understood. We hypo...